Canna x generalis irrigated with greywater in a nature-based solution

Image To achieve Goal 6 of the 2030 Agenda for Sustainable Development and provide water for all, water reuse is essential. We assessed the potential of treating greywater (LGw) while reusing it via irrigation of Canna x generalis, commonly used in nature-based solutions (NBS), with a view on plant development. The study was conducted at a mesocosm scale with factorial designs to test two substrates and four types of irrigation water. Stage 1 tested LGw, LGw with nutrients (LGw + N), and tap water with nutrients (TW + N). Stage 2 tested indoor and outdoor applications of TW (TWi and TWo, respectively) and LGw (LGwi... Read More

Managing Kidney Surgical Complications in Pregnant Women with Pre-existing Kidney Disease

Image Pregnancy can put a significant strain on the body, and women with pre-existing kidney disease are particularly vulnerable to kidney surgical complications. These complications can have serious consequences for both the mother and the developing fetus, highlighting the need for careful management and monitoring during pregnancy. One common complication is acute kidney injury (AKI), which can occur due to the stress of surgery, changes in blood flow, or exposure to contrast dye. AKI can lead to reduced kidney function, electrolyte imbalances, and in severe cases, kidney failure. This can have a direct impact on the health of the... Read More

Antiproliferative anthracycline pink red-like pigments produced by new bacterial soil strains identified as Streptomyces coelicoflavus .!

Image Among 29 soil isolated actinomycetes, five new strains MFB11, MFB20, MFB21, MFB23 and MFB24 showed an intracellular hydrophobic pink red-like pigment production. These pigments present similar physio-chemical characteristics with anthracycline antibiotics of prodigiosin family. Crud extract and prepared fractions were tested by MTT on mice cancer cell line as well on human cancer cell line. The results indicated an important antiproliferative effect of the different strain pigments on the two organism cell types. Human cells were more sensitive to the pigments and presented different antiproliferative... Read More

Effective marketing priority socialised

Image Social media marketing is one of the most popular types of marketing strategies. And, it's also one of the most effective to build awareness and increase sales. And it's not hard to understand why when more than 2.8 billion people use social media platforms.... Read More

Radiology vs interventions

Image Diagnostic radiology diagnoses diseases and injuries using imaging technologies, while interventional radiology involves performing procedures such as biopsies, catheterizations, and angiograms to diagnose and treat conditions.... Read More

Properties of Organometallic Chemistry

Image Description Organometallic compounds by definition contain somewhere around one carbon metal covalent bond. There is a wide variety of these compounds; simple alkyl metal compounds like tetraethyllead, 2-alkene compounds like Zeise's salt, and 3-allyl compounds like allylpalladium chloride dimer are examples of major classes metallocenes containing cyclopentadienyl ligands and carbene complexes of transition metals. There are numerous metal carbonyls and metal cyanides, such as potassium ferricyanide and tetracarbonylnickel. Metal carbonyl and cyanide complexes without additional carbon ligands, according to some researchers, are not organometallic but rather pure inorganic. However, the majority of organometallic chemists consider metal complexes with any carbon... Read More

Endometrial Cancers in Rural Women Population in Indian Geography: Histological Cue

Image Compared to western women population, the women folk in India are quite different inbeing more vulnerable to reproductive or gynecologic cancer for the following reasons. Most of the uterine cervical cancer patients in India belong to rural communities. The rural women are unaware of Pap smear test.  Awareness about hormone assay for estrogen and progesterone among the post-menopausal women is totally lacking. These women are also ignorant or careless about self-hygiene of sexual parts or regions. Sexual promiscuity among the male partners being more common the wives of these men are at high risk. For gynecologic cancers, sexually transmitted causative microbes... Read More

A short Note on Interactions between the Hormonal Proteins and Neurological Disorders

Image Functional neurologic disorders (FND) represent Associate in Nursing progressively frequent reason for incapacity and reduced independence; primary FND and practical symptoms overlapping with different neurologic diseases ar diagnosed in five-hitter and half-hour of cases, severally. Practical resonance imaging (fMRI) studies have recommended impaired top-down regulation of action choice, however pathophysiology of FND continues to be debated. Establishing the proper identification is usually delayed, resulting in extra, pricey and induced consequences. In clinical observe, practical muscle weakness (also said as motor mental disturbance, divisible motor disorder or ‘psychogenic’ disfunction) describes genuinely seasoned paralysis within the absence of neurological... Read More

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Image qqZZvK zoqjkswlwoux, [url=http://naprjdxwioml.com/]naprjdxwioml[/url], [link=http://bfthrufsrzcp.com/]bfthrufsrzcp[/link], http://wyerdymdmzfd.com/... Read More

Restoration in northern Lake Gehu ...!!!

Image Lake Gehu is a severely eutrophic lake in southeast China. A series of restoration measures have been implemented since 2009 in northern Lake Gehu. This study compared aquatic plants, water quality, sediment, and phytoplankton between restoration and control areas to investigate the effect of restoration measures. The results demonstrated that aquatic macrophyte coverage increased from 0% to 10.6%; mean TP, TN, and CODMn concentrations increased by 50.0%, 42.4 %, and 40.8%, respectively, compared with those before the measures were carried out; the mean Secchi depth... Read More

Monitoring of Ecosystem Metabolisms through remotely and Proximally Sensed ...!!!

Image The ability to predict the biogeochemical consequences of our actions for global climate failed as with the case of predicting many major natural, social, political or financial events throughout the human history. These unforeseen changes have been triggered by the interaction of many root causes such as unpredictable stochastic events, epistemological uncertainty, and lack of data to gauge the potential for changes to take place. In its constant and systematic search to be less wrong, however, the science strives for integrative and... Read More

An Analysis of Impact on Exports on Account of Tax Relief Measures To Sez & Export Oriented Units

Image Export plays an import role to determine the Balance of Payment (BOP) as well as the heath of overall economy of the nation. A favourable Balance of Payment (BOP) is always regarded as good sign for the economic development of the country and this can happen by means of increasing in exports. In this context several tax relief measures have been adopted by the government for several export oriented units over the number of years, in order to improve the situation of export and consequently the position of Balance of Payment (BOP). Out the several tax relief measures, the... Read More

The invention and production of a corona virus vaccine.

Image The invention of a vaccine is a complex and challenging process, which differs form the development ofo rdinary medicines. The normal time period for development of a vaccine is 12-15 years [1-3]. While the ordinary medicines are oriented towards the treatment of a disorder whose symptoms have arisen, vaccines are prepended for use in persons not yet exhibiting diseasem anifestation, in order to prevent the occurrence of diseases. The invention and production of a corona virus vaccine is a critical issue, but it is likely to take many months to resolve.... Read More

Infections of the eyes, ears and central nervous system

Image Eyelid infections generally involve the lid margins, eyelid glands or follicles causing styes or hordeolums. They are usually associated with Staphylococcus aureus infections. The conjunctiva is particularly susceptible to infection. The epithelial surface enclosed by the eyelids is a warm moist enclosed environment in which microorganisms can rapidly become established. However, microorganisms must avoid being rinsed away by tears and some pathogens, such as Chlamydia trachomatis, attach specifically to conjunctival cells. An estimated 500 million people are infected with different serotypes of Chlamydia trachomatis, making trachoma the most significant eye infection worldwide. The disease blinds approximately 1% of infected... Read More

Successful Weight Loss Before Bariatric Surgery as an Indicator for Perioperative Complications, Adherence, And Postoperative Weight Reduction A Retrospective Analysis

Image Objective: Participating in a weight loss program before bariatric surgery is an established preparation tool in many specialized bariatric clinics. A certain amount of weight loss before surgery can even be a mandatory requirement for some clinics or insurance companies. The objective of this study is to investigate whether successful preoperative weight loss through adherence to a low-calorie diet three weeks prior to bariatric surgery could predict a difference in the duration of the procedure, intraoperative blood loss, need for revision, excess weight loss after 12 months and the participation in postoperative follow-up visits. Methods: All cases that underwent... Read More

Dolichous biflorus Linn, Popularly known as kulthi belongs to family fabaceae

Image Dolichous biflorus Linn. Popularly known as kulthi belongs to family fabaceae. It is also known by its medicinal properties, it is one of the most effective ayurvedic medicines for treating kidney stones. Its diuretic, anthelminthic properties make it an ideal drug for urinary and digestive disorders. Pharmacognistical standardization of Dolichous biflorus seed has been carried out in the present study. The study includes macroscopic evaluation along with estimation of its physicochemical parameters, preliminary phytochemical screening, estimation of total phenolics and flavonoids as well as fingerprint profile by HPTLC, HPLC and GCMS. Determinations of contaminants... Read More

The analysis uncovered the facticity.

Image Carollyne Gomes de França Valle, Ines Silva de Almeida, Ann Mary Machado Tinoco Feitosa Rosas, Angela Maria e Silva To uncover the meaning of the first sexual intercourse to the adolescent. Descriptive and qualitative study with a phenomenological approach guided by Martin Heidegger references. The background/scenario used is (was) the first response ambulatory specialty clinic at the Nucleus of Teenage Health Studies (Núcleo de Estudos da Saúde do adolescente or NESA) at Rio de Janeiro State University (Universidade do Estado do Rio de Janeiro, UERJ). Data were collected in January and March of 2014.... Read More

A Short Note on Cancer Genetics

Image Oncogenes are also known as cellular genes that when mutated or potentially improperly communicated in a way that expands their action bring about a malignant phenotype. Traditional models incorporate src, ras and myc oncogenes. These genes are a lot of the vital parts of cell administrative cycles eg. The src quality is codes for a tyrosine kinase, the rash quality for a G protein and the myc quality for an atomic protein that is associated with DNA replication. Oncogenes were first found in intensely changing retroviruses (Rous Sarcoma Virus). When these infections taint deified however untransformed cells in... Read More

The Role of ThGM Cells as a Marker for Predicting Coronary Heart Disease

Image A range of immune cells and inflammatory mediators are involved in the chronic inflammatory illness known as Coronary Heart Disease (CHD). The origin of CHD is unknown, and its pathophysiology is complex and varied. To maximize the advantages of medical intervention, early-stage CHD must be detected. It has been suggested that CD4+T cells, macrophages, neutrophils, high-sensitivity C-reactive protein, IL-6, and GMCSF play a part in the onset and progression of CHD. The condition necessary for CHD is atherosclerosis. Immune cells from the blood, such as mast cells, macrophages, and T lymphoid cells, make up the majority of atherosclerotic plaques.... Read More

How should we Prepare for Post-COVID-19 ILD

Image Post-COVID-19 ILD is not a rare pathophysiology. Corticosteroid therapy may improve prolonged respiratory symptoms, hypoxemia, and radiographical abnormalities. Coronavirus disease 2019 (COVID-19) is a global problem. Globally, there have been more than 300 million confirmed COVID-19 cases and more than 5 million deaths. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is known to cause severe acute pneumonia, while the clinical courses vary. Post COVID-19 Interstitial Lung Disease (ILD) is considered to be “Long COVID”, which is of great interest because it causes patients’ disabilities, and the mechanisms, clinical course, and treatments have... Read More

Economic Evaluation of Chickenpox Vaccination

Image Chickenpox is an infectious disease that causes skin rashes. This disease is caused by a bacterium called the varicella zoster virus. Chickenpox itself is also called varicella zoster. Most people get the virus when they are young if they have not been vaccinated against chickenpox. Children with chickenpox can easily transmit the virus to other children. Chickenpox is much less common today as most children are vaccinated at a young age. Before the first chickenpox vaccine was approved in the United States in 1995, most people got chickenpox. Few had complications. If we have not been vaccinated, we... Read More

Tunable Dual-phase Dual-drug Delivery System using a PLGA Micro particle/PVA Hydrogel Composite

Image Current Drug Delivery Systems (DDSs) have demonstrated controlled long-term, sustained release but have only tried to diminish burst release. For applications like wound healing, there is a need for a DDS which is adjustable in both short- and long-term release, independent of each other. We present a tunable dual-phase dual-drug delivery system composed of drug-loaded polymer micro particles and drug-loaded hydrogel in this study. This system was created using lidocaine and dexamethasone encapsulated in poly (D,L-lactide-co-glycolide) particles combined with lidocaine- and dexamethasone-loaded poly(vinyl alcohol) hydrogel. Hydrogel drug concentration and micro particle mass fraction were investigated for... Read More

Cerebral Spinal Fluid (CSF) Analysis in Corona Virus Patients

Image The rise of extreme intense respiratory condition COVID 2 (SARS CoV-2) in Wuhan, China, this exceptionally contagious infection has since spread quickly all over the planet. However respiratory entanglement is the basically revealed appearance however intriguing, yet genuine neurological confusions are by and large as often as possible detailed in the writing. In chose COVID sickness 2019 (Coronavirus) cases neurologic complexities might appear as seizures. In this paper, we have explored current writing on seizures connected with SARS-COV 2 disease including distributed or pre-print unique articles, survey articles, and case reports. We have talked about the Electroencephalogram... Read More

Paediatrics

Image Child Health is an authoritative and comprehensive resource that provides all paediatricians and child health care specialists with up-to-date reviews on all aspects of hospital/community paediatrics and neonatology, including investigations and technical procedures.... Read More

Treatment of gout flares

Image A gout flare is an intensely painful and disabling inflammatory arthritis, usually involving a single joint but occasionally involving two or more joints. The goal of therapy in a gout flare is prompt and safe termination of pain and disability. Without therapy, the gout flare usually resolves completely within a few days to several weeks, particularly in early disease. However, symptoms improve more quickly with administration of any of a broad array of antiinflammatory drugs Upon resolution of a gout flare, the patient is said to have entered a symptom-free (interval, intercritical, or between flares) period. However, flares... Read More

Heterotrophic epiglottic lymphoid tissue may be considered a newly described.

Image A unique case of recurrent infectious epiglottitis in an immunocompetent, fully immunized, non-syndromic 23 year old female. Method: Case report Results: Patient was successfully managed with an endoscopic partial epiglottectomy at two years of follow-up. Pathology revealed what appears to be sub-mucosal germinally-active heterotropic lymphoid tissue within the epiglottic soft tissues as the likely cause of the recurrent epiglottitis. Conclusions: The embryology of the lingual tonsils and epiglottis may provide a clue to the etiology of this case. Heterotrophic epiglottic lymphoid tissue may be considered a newly described, clinically significant congenital... Read More

Assessment of Cellular Responses to Oxidative Stress using Breast Cancer Cells

Image The combination and role of oxidative stress and antioxidants in vivo is still a matter of conjecture. Our objective for the present study was to expose MCF-7 breast cancer cells in vitro (as a chronic disease example) to aqueous and alcohol extracts and in combination with H2O2 as an oxidative stressor. Measurement of cell survival under various concentrations and mixtures was conducted using standard cell culture techniques, exposure protocols in 96 well plates and Fluorospectrosphotometry. Following cellular growth to 90% confluence, exposure to water (WE) and ethanol (AE) extracts of N. sativa and H2O2 was performed. Cell... Read More

Pakistani type 2 diabetes mellitus (T2DM) patients.

Image Diabetes mellitus (DM) is a health concern because it leads to complications such as retinopathy and nephropathy. Pakistan has 6.9 million DM affected people that will be doubled by 2025. A study was designed to determine the role of genetics in diabetic retinopathy in Pakistani type 2 diabetes mellitus (T2DM) patients. It was a cross-sectional case-control study that included 236 subjects, divided into Group I (54 volunteers without diabetes), Group II (30 T2DM patients without retinopathy) and Group III (152 T2DM patients with retinopathy). A BglII polymorphism of α2β1 integrin gene was genotyped in all these individuals... Read More

Prevalence of Extended Spectrum Beta-lactamase Producing Enterobacteriaceae: A Cross Sectional Study at Adama Hospital, Adama, Ethiopia:-

Image The beta-lactam groups of antibiotics are the largest group of antibacterial agents used in clinical practice and they are frequently prescribed. The wide use of these antibiotics leads to the emergence and spread of resistant bacterial pathogens that produce the extended-spectrum β-lactamases (ESBL). Now days ESBLs producer bacteria are a common encounter in clinical practice and their prevalence varies from local to global. The aim of this study was to determine the prevalence of ESBL producing bacterial pathogens among Enterobacteriaceae isolates at Adama Hospital, Ethiopia. Methods: Across sectional study was conducted from May 1, 2013-June 1, 2014 at... Read More

Prevalence of Extended Spectrum Beta-lactamase Producing Enterobacteriaceae: A Cross Sectional Study at Adama Hospital, Adama, Ethiopia:,

Image The beta-lactam groups of antibiotics are the largest group of antibacterial agents used in clinical practice and they are frequently prescribed. The wide use of these antibiotics leads to the emergence and spread of resistant bacterial pathogens that produce the extended-spectrum β-lactamases (ESBL). Now days ESBLs producer bacteria are a common encounter in clinical practice and their prevalence varies from local to global. The aim of this study was to determine the prevalence of ESBL producing bacterial pathogens among Enterobacteriaceae isolates at Adama Hospital, Ethiopia. Methods: Across sectional study was conducted from May 1, 2013-June 1, 2014 at... Read More

Prevalence of Extended Spectrum Beta-lactamase Producing Enterobacteriaceae: A Cross Sectional Study at Adama Hospital, Adama, Ethiopia:

Image The beta-lactam groups of antibiotics are the largest group of antibacterial agents used in clinical practice and they are frequently prescribed. The wide use of these antibiotics leads to the emergence and spread of resistant bacterial pathogens that produce the extended-spectrum β-lactamases (ESBL). Now days ESBLs producer bacteria are a common encounter in clinical practice and their prevalence varies from local to global. The aim of this study was to determine the prevalence of ESBL producing bacterial pathogens among Enterobacteriaceae isolates at Adama Hospital, Ethiopia. Methods: Across sectional study was conducted from May 1, 2013-June 1, 2014 at... Read More

Role of Postharvest Management for Food Security: A Review.

Image The primary role of an effective post-harvest handling system is ensuring that the harvested product reaches the consumer, while fulfilling market/consumer expectations in terms of volume, quality, and other product and transaction attributes, including nutrition, food security, and product safety. The aim of this review was how to manage postharvest losses of crops for food security. Postharvest losses of crops commodities were managed or controlled by doing proper harvesting, transportation, packing, storage, processing, sorting and cleaning. Thus, reduction of post-harvest food losses is a critical component of ensuring future global food security.... Read More

Hemoglobin A1c (HbA1c) is the current standard used in the clinical treatment of patients with diabetes.

Image Hemoglobin A1c (HbA1c) is the current standard used in the clinical treatment of patients with diabetes. However, it has been shown that patients with similar HbA1c values may have widely different fluctuations in blood glucose values over the same period of time, including time spent in hyper- and/or hypo-glycemia. Hence, there exists a need for quantitative measures that can supplement HbA1c in managing patients with diabetes. We introduce and compare the Dynamic Stress Factor, DySF, a newly developed metric that quantifies glycemic volatility based on patient-specific glucose transition density profiles with HbA1c and with... Read More

Transformation of Bacterial Genome Design

Image Bacteriology is the conventional branch of Microbiology, which focuses on basic microbiology, host-pathogen interactions, biochemistry, molecular biology and mechanisms, ecology and epidemiology of bacteria. Parasitology is a closest relative of Medical Microbiology that encompasses the parasite world ranging from protozoans to helminthes. The Journal of Bacteriology & Parasitology is specialist journal, which is known for its state-of –the –art presentation of the latest discoveries in Bacteriology and Parasitology. Transformation of Bacterial Genome Design When bacteria and eukaryotes are subjected to genetic drift, their genome architecture evolves in opposing ways, owing to the fact that bacteria have a mutational bias... Read More

Multi-TPMS lattice structure

Image The distinctive topology-driven skillfulness of natural biological systems has intended the fabric science analysis community to style and synthesize architected cellular materials for various engineering disciplines. However, the lattice cell style of architected cellular materials is extremely discretionary, creating the planning of architected cellular materials terribly troublesome. So as to beat these issues, associate degree innovative triple amount lowest surface (TPMS) lattice kind distribution rule supported the most strain energy principle is planned during this paper to optimize the stiffness of the structure. The rule establishes the mapping relationship between the denseness of TPMS lattice cells and... Read More

Insulin resistance plays an important role in the pathogenesis

Image Insulin resistance plays an important role in the pathogenesis of type2 diabetes and the metabolic syndrome. Many of the genes and pathways involved have been identified but some remain to be defined. Metallothioneins (Mts) are a family of anti-oxidant proteins and metallothionein 2a (Mt2a) polymorphims have been recently associated with type 2 diabetes and related complications. Our objective was to determine Mt2a gene expression levels in adipose tissues from diabetic patients and determine the effect of Mt treatment on adipocyte insulin sensitivity. Methods: Samples of subcutaneous and visceral adipose tissues from lean, type 2 diabetic and non-diabetic obese... Read More

Polymorphisms are associated with type 2 diabetes mellitus (T2DM).

Image This paper describes a case-control study and a meta-analysis conducted to determine whether the TLR4 Asp299Gly (rs4986790) and Thr399Ile (rs4986791) polymorphisms are associated with type 2 diabetes mellitus (T2DM). In the case-control study were enrolled 1683 T2DM patients and 584 nondiabetic subjects from Brazil. A literature search was conducted in order to identify studies that investigated associations between the referred TLR4 polymorphisms and T2DM. Pooled odds ratios (OR) were calculated for allele contrast and dominant inheritance models. Results: In the case-control study, genotype and allele frequencies of the Asp299Gly and Thr399Ile polymorphisms differed between... Read More

Nine months after this injury, he presented to our clinic with dysphagia, aphonia, and tracheotomy dependence.

Image To describe an unusual case of a denture retained in the oropharynx for one year and highlight current management of airway foreign bodies. Study design: A case report and brief review of the literature. Results: A 27 year old man sustained a gunshot wound to the neck and underwent exploratory surgery and tracheotomy at an outside hospital. Nine months after this injury, he presented to our clinic with dysphagia, aphonia, and tracheotomy dependence. Normal anatomic landmarks were not visible by indirect laryngoscopy and imaging suggested a possible plate-like prosthesis in the oropharynx. Diagnostic direct... Read More

All the selected cases underwent otological examination by clinical examination f

Image The aim of this study is to determine the pattern of hearing loss in otological trauma due to non-explosive trauma caused by slap in Kashmiri population. The study was conducted in otolaryngology clinic of a referral and a teaching tertiary care hospital Sher-i-Kashmir Institute of Medical Sciences Medical College, Bemina, Srinagar, Jammu and Kashmir, where 569 cases with non-explosive blast injury of the ear due to slap, gathered over a 3-year period, is presented. 522 Patients fulfill the inclusion criteria and 47 cases were excluded. All the selected cases underwent otological examination by clinical... Read More

Compostable Bioplastic Food Packaging and Foodservice

Image Incorporated into institutional and corporate sustainability programmes, compostable bioplastic food packaging and foodservice ware is gaining popularity as a replacement for plastics derived from petroleum. Compostable bioplastics, on the other hand, come with their own unique set of complex issues and constraints that affect sustainability throughout their lifecycle. In some cases, these issues and limitations may even prevent the adoption of sustainable waste management techniques and, consequently, the growth of a circular economy. This study examined, from a systems viewpoint, the opportunities and constraints of biodegradable bioplastic food packaging and foodservice... Read More

: Mercury Toxicity Can Be Lethal

Image Mercury poisoning is very common now days. We see it everywhere if we consume a lot of marine fish. Mercury is also present in some of the products that we often use in our homes, offices, dental clinics & at other places. We need to take adequate action to deal with mercury poisoning to curb this menace. Mercury poisoning can be lethal if it exceeds the normal mercury content in the human body. The total mercury concentration in whole human blood is usually lower than10 μg/L, but if the value of... Read More

An Irregular, Double-Blind, Placebo-Controlled Proof of Construct Study to Guage Samidorphan within the Bar of Olanzapine-Induced Weight Gain in Healthy Volunteers...

Image Antipsychotic medications square measure related to weight gain and adverse metabolic effects that complicate the treatment and management of dementia praecox. Olanzapine (OLZ) specially is related to important weight gain and adverse metabolic effects. this section one, proof of conception, multicenter, randomized, double-blind,placebo-controlled study investigated the security and result on weight of a mix of OLZ (10 mg) and also the opioid modulator samidorphan (SAM; five mg) compared to OLZ alone in healthy, male traditional weight volunteers.Altogether, 106 male subjects with stable weight and BMI 18–25 kg/m2 were irregular to OLZ alone, OLZ + SAM,SAM alone, or placebo in... Read More

Implementation of Modern Technologies in Palliative Care to Address Structural Problems in the Management of Neurological Patients

Image  Telemedicine offers a way to deal with the health-care system's scarcity of resources and money. Although palliative care has been advised for an increasing number of patients with neurodegenerative illnesses, these patients frequently lack access to either palliative care or neurology. Palliative care is a multidisciplinary approach, thus using palliative care structures as a foundation makes sense. In an outpatient context, there is no systematic access to neurological expertise. A palliative care strategy has the potential to identify and enhance key patient and caregiver outcomes. As a relatively new use of palliative care, research is needed to adapt,... Read More

Detection of Borrelia burgdorferi in a Sick Peregrine Falcon (Falco peregrinus)-A Case Report

Image Borrelia (B.) burgdorferi, the causative agent of Lyme disease, is the most important zoonotic pathogen in the northern hemisphere. This report describes a peregrine falcon (Falco peregrinus) infected with B. burgdorferi. The patient was presented with a swollen intertarsal joint, diarrhoea, and a reduced general condition. Radiographs were inconspicuous. Antibacterial treatment against the bacterium Escherichia coli found in the intestine and joint did not lead to success. The serological testing for B. burgdorferi was positive. The bird recovered well after a therapy for borreliosis similar to that in humans and mammals. In future, it should be taken into account that... Read More

An Educational Intervention with Hispanic HIV Infected Patients: A Randomized Study.

Image Background: Patient’s knowledge of their disease has been associated with better ART adherence however, little is known on the effects of increased knowledge on health outcomes in Hispanics. We tested the ability of a structured, culturally sensitive Educational Intervention (EI) to improve HIV knowledge and clinical outcomes of Hispanic HIV patients. Methods: 400 Hispanic HIV positive patients were enrolled from HIV clinics in Miami; FL. Patients were randomized to a Standard of Care (SOC) HIV management and SOC plus the EI. The EI consisted of 3 two-hour modules delivered over 12 weeks. HIV knowledge and CD4 cell counts... Read More

Complementary and Alternative Medicine (CAM) and the Public Health: an Innovative Healthcare Practice in Supporting and Sustaining Health and Well-Being

Image Objectives: Lateral epicondylitis (tennis elbow) is a tendinosis of the forearm extensor muscles; it has a clear occupational profile. Epicondylitis usually improves with conservative treatment but some 10% of cases require more invasive therapies, such as shock waves, infiltration with steroids or growth factors. Although its mechanism of action is unknown, pulsed radiofrequency appears to improve the patient’s perception of pain. In recent years, this has been used in peripheral pathologies with promising results. This study evaluates the efficacy of two different patterns of radiofrequency for treating epicondylitis. Materials and methods: This was a comparative study of 34 patients, divided randomly intotwo groups: Group A... Read More

The Rural Aged and their Health: A Poverty-Health Viewpoint

Image Introduction: In Jamaica, rural poverty is twice that of urban poverty with about 50 percentage points of elderly residing in rural zones. Poverty is not only a measure of the economic reality; it is also a critical driver of the health challenge being experienced by this vulnerable group. Objectives: The present study aims to 1) evaluate health of rural elderly, 2) determine factors that influence selfrated health status of the rural aged, 3) determine factors of self-reported illness among rural aged in Jamaica, and 4) examine the changing patterns of diseases of the rural aged Jamaicans over a 5-year period.... Read More

Is Achieving Undetectable Viral Load in the CNS Reservoir an Important Benchmark for Curing HIV Infection?.

Image Viral reservoirs present a formidable challenge in our search for a cure of human immunodeficiency Virus (HIV) infection. It is widely known tthat combined antiretroviral medications do not access the central nervous system (CNS) at optimal levels. Recent experience with hematopoietic stem cell transplant technology highlight both the need to purge the CNS reservoir from latent HIV-infected macrophages and microglia, and the requirement for utilizing homozygous CCR5Δ32 allele in successfully curing HIV infection and progression to acquired immunodeficiency syndrome (AIDS). These developments bring into focus the need to study additional alleles that affect disease progression, neurocognitive status, and potential viral egress from the CNS.... Read More

Human Rights Law

Image Human rights are rights inherent to all human beings, whatever our nationality, place of residence, sex, national or ethnic origin, colour, religion, language, or any other status. We are all equally entitled to our human rights without discrimination. These rights are all interrelated, interdependent and indivisible.... Read More

Kaposi Sarcoma Pathogenesis: A Triad of Viral Infection, Oncogenesis and Chronic Inflammation

Image Kaposi sarcoma (KS) is a complex cancer that arises from the initial infection of an appropriate endothelial or progenitorcell by Kaposi Sarcoma Herpesvirus/Human Herpesvirus-8 (KSHV/HHV8). However, the majority of KS cases occur wheninfected patients also suffer from some coincident form of immune deregulation, providing a favorable microenvironmentfor tumor development. Cellular hallmarks of KS progression include both the hyper-proliferation of KSHV-infectedcells and the infiltration of immune modulatory cells into KS lesions, which together result in chronic inflammation,the induction of angiogenesis and tumor growth. This review describes the current understanding of the interactionsbetween KSHV and host responses that result... Read More

A Rare Presentation of Community-acquired Pneumonia Caused by Corynebacterium pseudodiptheriticum: A Case Report.

Image Background: Â As a normal flora in the upper respiratory tract, Corynebacterium (C.) pseudodiptheriticum is not often considered as the causative bacterium for community-acquired pneumonia. Findings: In this case report, a patient with bronchiectasis was initially suspected as being infected with Mycobacterium avium. When antibiotic treatment was not successful, bronchial alveolar lavage was obtained for microbiological culturing. Once C. pseudodiptheriticum was recovered from this less-frequently requested respiratory sample, its antibiotic susceptibility profile was obtained to allow appropriate antimicrobial intervention to arrest the infection. The patient experienced full recovery. Conclusion: This report shows the importance of considering non-routine, sometimes invasive clinical specimens to make a diagnosis. Furthermore,... Read More

The Structures of the Supermolecule that Binds the Orf Virus Chemokine in Conjunction with the Host Chemokines are used to Infer Broad Binding Specificity

Image Chemokines play necessary roles inside the system, not entirely recruiting leukocytes to the situation of infection and inflammation but collectively guiding cell orienting and cell development. The soluble poxvirus-encoded organic compound infective agent CC chemokine substance (vcci), a CC chemokine substance, can bind to human CC chemokines tightly to impair the host immune defense. This organic compound has no well-known homologs in eukaryotes and can represent a potent methodology to forestall inflammation. Previously, our structure of the vcci MIP-1β (macrophage inflammatory protein-1β) difficult indicated that vcci uses charged residues in β-sheet II to act with charged residues inside the... Read More

Occupational Medicine and Health Affairs Interest

Image My interest in occupational medicine and related health affairs stems from both professional and personal perspectives. Professionally, the capacity to physically perform work in an effective and efficient manner has always been curious to me. Whether a person is a first responder, carpenter or someone performing filing, the ability to physically accomplish the task in a given amount of time, without being overly fatigued, is important not only to the worker, but the employer and the health system. Physical tasks that result in abnormal physiological responses could eventually contrib pathologicute to tendencies. Pathology, which could in time result... Read More

Some Health Disorders among Workers in a Glass Factory

Image Introduction: The common Health hazards associated with glass manufacturing processes include noise, exposures to respirable airborne particulates [especially silica (SiO2) that leads to chronic effects such as decreased pulmonary function, lung disease, complicated pneumoconiosis (silicosis, the most important and oldest occupational lung diseases worldwide specially in developing countries) and silico-tuberculosis], ergonomic hazards, physical hazards, radiant energy, heat stress disorders and infrared radiation. Aim of the study: Studying some health disorders among Egyptian workers in a glass industry as well as to assessing workplace environment in the same factory. Participants and methods: A cross sectional comparative study was carried... Read More

Predictors of Intention to Quit Cigarette Smoking among Jordanian Adults

Image Objective: Having an intention to quit smoking is associated with quitting and is a step toward the required behavioral change. This study examines the predictors of an intention to quit and predictors of previous quitting attempt in a sample of adult Jordanian smokers (n=260). Methods: A cross-sectional study in a convenient sample of willing adults in Amman, Jordan (n=600). The survey included socio-demographic characteristics, history of tobacco smoking, environmental and behavioral determinants of smoking like peer influence, and perceived harm. Individuals who smoked a cigarette during the previous month were considered smokers and included in further analysis (n=260). Three... Read More

CXCR4 inhibitor plerixafor and G-CSF allow for an effective peripheral blood stem cell collection in patients who failed previous mobilization attempt

Image Plerixafor is a CXCR4 receptor inhibitor, which was recently introduced for stem cell mobilization in myeloma and lymphoma patients prior to their transplantation. Since March 2009, we performed 16 mobilizations using plerixafor in combination with G-CSF in 10 patients with multiple myeloma, 3 Non-Hodgkin’s lymphoma and 3 Hodgkin’s lymphoma, who failed previous mobilization attempts with G-CSF in combination with chemotherapy.... Read More

Translational Biomedicine: a clinician view

Image If I have to name the most momentous concept for biomedicine in the last decade, I would certainly go for the term “translational” without any hesitation. Not only it describes the vast array of biomedical research activities that relate to the study of human disease, their treatment and prevention; it also directs the processes of novel drug discovery and medical devices invention that directly or indirectly affects our economy as a whole.... Read More

The Association between Low Back Pain and Fatigue among Commercial Drivers

Image Objective: To examine the association between low back pain and fatigue among commercial drivers. Methods: A self-selected group of 90 current commercial drivers from 3 locations participated in an anonymous survey. Low back pain was assessed by the Oswestry Disability Index (ODI). Fatigue was measured by the Brief Fatigue Inventory. Multiple linear regression (MLR) was used to quantify the association between LBP and fatigue. Results: MLR showed that increased level of low back pain is a significant predictor of increased fatigue when adjusted for age, gender, BMI, job satisfaction, years and miles driven (p<0.001). Conclusion: These results... Read More

A New Forum for Exchanges across Many Fields Relating to Occupational Health and Medicine

Image  The intent of launching a journal in this area is to integrate several aspects of occupational medicine and health. These include mechanistic, regulatory, epidemiological and public health perspectives of workplace issues. By putting such a range of viewpoints all under one roof, it is hoped to further cross talk between disciplines that would be otherwise not possible in other platforms such as forum. Occupational health is often the cornerstone of progress in public health and epidemiology as it is in the workplace that a well-defined relatively homogeneous population can be studied. Ensuring protection of worker’s health is a... Read More

Effect of Covid-19 on Diabetes Mellitus with the Metabolism based on Glucose

Image Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been discovered to influence this respiratory system of people with DIABETES Mellitus, such as acute respiratory syndrome coronavirus. After predisposing patients to severe COVID 19, a patient with diabetes mellitus already has a weakened immune system. However, preliminary findings suggest that glucose-lowering DPP4 inhibitors have no effect on SARS-COV-2 vulnerability. In sufferer with COVID-19 and s, sodium-glucose co transporter 2 (SGLT2) inhibitors may have a severe effect due to their pharmacological properties.... Read More

How Important is Vitamin D in Covid-19?

Image A novel coronavirus disease that wreaked havoc throughout 2019 caused universal outrage and threatened our way of life and our existence. Given the tremendous impact of the Corona pandemic, any method for improving patients' conditions, accelerating recovery, and reducing the danger of worsening and mortality, would be regarded of critical clinical and economic importance. In most nations, the Coronavirus Disease 2019 (The Disease) havoc remains a severe health danger. In individuals, the COVID virus (SARS-CoV-2) can cause ARDS like symptoms (acute respiratory distress syndrome) which may finally result in death. Vit D is an Immuno modulator hormone that... Read More

Effect of Rising Temperatures and Climate Change on Neurological Disorders

Image Brain disorders such as neurological, psychiatric, and developmental now have an effect on at the least 250 million people in the developing world, and this range is anticipated to rise as life expectancy will increase. Yet public and private health systems in developing countries have paid especially little interest to brain disorders. The negative attitudes, prejudice, and stigma that regularly surround lots of these disorders have contributed to this neglect... Read More

Trends in Maternal Mortality, Socio-Economic Status, Rights and Responsibilities to Reduce Maternal Deaths

Image The COVID-19 pandemic together with the growing racial justice movement has highlighted longstanding disparities in health and health care for people of color, including stark disparities in maternal and infant health. Despite continued advancements in medical care, rates of maternal mortality and morbidity and pre-term start have been rising in the U.S. Maternal and infant mortality rates in the U.S. are far better than those in similarly large and wealthy countries, and people of color are at increased risk for poor maternal and infant health consequences ... Read More

Hurry up !! Last issue release||Submit your manuscripts and grab the opportunity

Image Hurry up !! Last issue release||Submit your manuscripts and grab the opportunity 694 nm red laser photons disrupt a static magnetic field and cause movement in organic paper material exposed to sunlight as proof that photons have a charge. By Rachel Haywood In Journal of Modern and Applied Physics (Volume 6 Issue 6) More about Photons It is accepted that photons, as they are represented by particle and wave theories, do not have mass, charge, or are not affected by a magnetic field. Hair containing melanin was exposed to a 694 nm laser during electron spin resonance tests. While observing... Read More

Association between Glaucoma and Diabetes

Image The optic nerve may be harmed as a result of the eye disorder Glaucoma. The health of your eyes depends on this nerve. Damage to it may result in blindness in certain situations and irreversible visual loss in other cases. Glaucoma is frequently brought on by high intraocular pressure. A risk factor for Glaucoma, however, might also be Diabetes. A risk factor for primary open-angle Glaucoma is type 2 diabetes. If a person is diagnosed with type 2 diabetes, an ophthalmologist should have been contacted to check for any symptoms of Diabetic retinopathy, a condition in which high... Read More

Causes, evaluation, and therapy for nyctalopia

Image Nyctalopia, often known as night blindness, is a type of vision impairment. Night blindness is characterised by difficulties seeing at night or in dimly lit areas. Although it is incorrect, the phrase "night blindness" indicates that person have trouble seeing at night. Perhaps driving or seeing in the dark is simply more difficult. Causes • Retinitis pigmentosa, which develops when dark pigment builds up in retina and causes tunnel vision, can cause several eye conditions, such as blurry vision when looking at distant objects cataracts or clouding of the lens, which can cause night blindness. • Usher's syndrome, a... Read More

Risk factors and symptoms for developing Strabismus

Image Visual acuity: An optometry doctor measures visual acuity to determine how much vision is impaired. For the test, patient will be asked to read letters on reading boards near and far. Visual acuity is written as a fraction, e.g. B. 20/40. The top number is the standard distance at which the test is conducted (20 feet). The bottom number is the smallest font size you can read at a distance of 20 feet. A person with 20/40 visual acuity would need to be within 20 feet of a letter that should be clearly visible 40 feet away. The "normal"... Read More

Incidence of Insomnia and Anxiety among the Biotechnology Students: A Cross-sectional Study at BUITEMS, Quetta

Image Objective: Anxiety and Insomnia is mostly seen in students engage in biological researches belonging to the life sciences or applied sciences discipline. Since biotechnology students are also engaged in extensive research work along with the stress associated with maintaining good grades, GPA, participating in extracurricular activities, completion of assignments, maintaining monthly attendance etc., signs of insomnia and anxiety are quiet prominent which affects their interpersonal and psychological functioning. Therefore, the aim of this study was to determine the incidence of insomnia and anxiety among the Biotechnology students of BUITEMS. Method: This study was conducted in BUITEMS among the biotechnology students.... Read More

Chronic Kidney Disease in Libya, Cross-sectional Single Center Study

Image Background: Chronic kidney disease (CKD) is a common problem globally and has heavy burden on patients and health authorities. Knowing the risk factors of CKD will reduce the prevalence of CKD and its socio-economic effects. Aim of study: To determine the risk factors that lead to CKD in Libyan patients. Method: Cross-sectional study based on single-center experience. Two-hundreds and four out-patient’s notes were reviewed. All were adults aged >18 years. Result: Records of 204 CKD patients were reviewed, 55.4% female and 91 (44.6%) patients were male. Patient’s mean age was 51.9 ± 15.7 years, and there was not significant difference between... Read More

Kinematic Causes and Exercise Rehabilitations of Patients with Round Shoulder, Thoracic Kyphosis and Forward Head Posture (FHP)

Image Purpose: To analyze the cause in kinematics and corresponding exercise rehabilitation of round shoulder, thoracic kyphosis and forward head posture. Methods: We recruited 26 patients with obvious symptoms of round shoulder, thoracickyphosis and forward head posture, with a difference of 4 degree or more in positive rake angle. Patients include 16 males with an average age of 24 ± 3.4 (Mean ± SD) and 10 females with an average age of 25 ± 3.7, with an overall duration of pathological symptoms of 3.4 ± 1.3 years. The sports prescription effectiveness was evaluated base on positive rake angle, neck vertebrae mobility and... Read More

Model for Rainfall and Malaria Cases in Yilmana Densa District, North West Ethiopia

Image Background: Malaria is the major public health problem in Ethiopia. Rain fall amount and distribution have impact for malaria transmission. Objective: To assess the relationship between positive malaria cases and Rainfall within ten year’s periodic trends of malaria transmission. Method: Retrospective study design was conducted by using ten years monthly rainfall and positive malaria cases. Simple linear regression, correlation were applied to analyze association. SPSS version 16.0 was used for analysis. Result: A slight variation of malaria transmission was observed in the last ten years and the transmission was non periodic. Among Plasmodium species, P. falciparum was highly prevalent. From spearman correlation... Read More

Clinical Risk Factors and Duration of Infectiousness of SARS-CoV-2 Among Symptomatic and Asymptomatic Patients

Image We have investigated the clinical characteristics, duration of infectiousness from onset of symptoms and viral kinetics among moderate, mild and asymptomatic cases. For 181 cases, clinical features that were statistically significant between moderate and mild cases are fever (p-value 0.028), cough (p-value 0.352), runny nose (p-value 0.016), nausea (p-value 0.039), loss of smell and taste (p-value 0.02 each), fatigue (p-value 0.008), muscle ache (p-value 0.004), loss of appetite (p-value 0.041) and contact history (p-value 0.010). Logistic regression showed fever (OR, 4.35; p-value 0.006), cough (OR, 12.38; p-value 0.0001), expectoration (OR, 7.54; 0.003), sore throat (OR, 8.50; 0.0001), SOB (OR,... Read More

Viral Dynamics and Ct Value Distribution with Age and Gender of COVID-19 Patients in a Tertiary Care Hospital Lahore, Pakistan

Image This was a retrospective study of 2,956 cases detected positive by RT-PCR to observe the viral dynamics in different age groups and gender using Ct value of COVID-19 patients, 78% cases were detected positive for ORF1ab and E gene, 15% cases were positive for ORF1ab and N gene while 8% cases were positive only for ORF1ab. The mean, median and 95% CI of Ct for ORF1ab were all numerically higher than the comparative value of E gene (mean, 27.26 vs. 26.31; median, 27.51 vs. 26.93 and 95% CI 26.92-27.60 vs. 25.98-26.63) p-value <0.0001 and N gene (mean, 35.22 vs. 29.58;... Read More

Immune Gene Prognostic Signature by Translational Research

Image Massive data sets and the development of artificial intelligence algorithms provide fresh perspectives and options for predicting cancer patients' unique mortality risks. The goal of the recently completed research was to construct an artificial intelligence survival prediction system for stomach cancer patients who were disease-free [1]. The artificial intelligence survival predicting system was created using the multi-task logistic regression algorithm, the cox survival regression method, and the random survival forest algorithm [2]. A transcription factor regulatory network of immune genes was created using 19 transcription factors and 70 immune genes [3]. Fourteen immunological... Read More

Synthetic Biology in Drug Discovery as a Source of Discovery in Translation Biomedicine

Image The declining cost of DNA synthesis, improvements in genetic engineering, expanding knowledge of genome organisation, and boom in data science, the influence of synthetic biology on the world has been escalating [1]. But a lot of the discipline's use in the pharmaceutical sector is still unclear. The influence of synthetic biology on target validation, assay development, hit discovery, lead optimization, chemical synthesis, and the creation of cellular therapies is highlighted in this review's current examples. We also emphasise the accessibility of the technology and resources powering the field [2]. All phases of drug discovery and development... Read More

A Case-Control Research Examined the Effect of Traumatic Oral Damage on Early Toddler's

Image There are no long-term research that examine how traumatic dental injury (TDI) affects preschoolers' oral healthrelated quality of life. A population-based case-control study was conducted with a representative sample of 335 children, ages 3-5, enrolled in public and private preschools in the city of Campina Grande, Brazil, to examine the effect of TDI on in preschoolers. Age, gender, type of preschool and monthly household income of the case group and the control group were matched at a ratio of one to four (67 cases and 286 controls). Application of the Early Childhood Oral Health Impact Scale allowed for... Read More

Working Conditions and Health in MENA Region During the Covid-19 Pandemic: Keeping an Eye on The Gap.

Image Background: The advent of the COVID-19 pandemic has had a significant impact on the workplace, both in terms of the number of cases among the working population and the massive modifications necessary to cope. Objectives: The purpose of this study is to assess the influence of COVID-19 on wage earners' working conditions and health in the Middle East and South Africa (MENA) region. Methods: Cross-sectional study was conducted between the mid of November and the end of December 2021 among the wage- earning population. Sample included n = 7555 participants obtained through an online survey. Results: Work post attendance was clearly... Read More

The Application of Nanotechnology in Microneedles for Drug Delivery

Image Microneedle (MN), a smart transdermal drug delivery system (TDDS), is a promising novel technology to deliver various drugs having different physicochemical properties. Such an approach and innovative technology attracted the attention of researchers worldwide to further study and discover the new technology due to the multiple advantages MN offers as it is a non-invasive TDDS with a fast onset of action besides sustained release properties. The combination of nanotechnology with microneedles’ technology presents an innovative and novel promising strategy aiming to merge the advantages of both technologies to allow safe and effective delivery with improved skin permeability of various... Read More

Debates and politics in safety science

Image Articles in all areas of political science, election tribunal, and related disciplines are regularly published in the open access, peer-reviewed Global Journal of Political Science and Election Tribunal (GJPSET). The purpose of this journal is to provide scientists and researchers from all over the world with a sincere forum for exchanging ideas, promoting research, and debating a wide range of cutting-edge ideas and developments in all areas of vocational and technical education. Submissions of manuscripts to the journal are encouraged as long as they meet the general standards for relevance and scientific excellence. The early works on organisational and... Read More

Non-Hygienic Practices and Its Implication on Students’ Health In College Of Health Sciences, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria

Image Hygiene refers to conditions and practices that help to maintain health and prevent the spread of diseases. It is important to live in an environment that is free of incidence of hazardous waste, its impacts is usually felt in all aspects of life of the individual having contact with that environment. This research examines non-hygienic practices and it's implication on students' health in College of Health Sciences, Niger Delta University, Wilberforce Island, Amassoma,Bayelsa State, Nigeria. Three research specific objectives were used alongside three research questions which have been raised with the aim of achieving the objectives. The main purpose... Read More

The importance of beach erosion, managing inlets and changing shorelines

Image Beach erosion on nearby beaches will be reduced through improvements in sand bypassing at inlets, which may also result in a future requirement for less beach nourishment. Over a million cubic yards of beach-quality sand have been dumped on the downdrift beaches of Jupiter Island as part of the recently approved St. Lucie Inlet Management Plan, which is located in Martin County, Florida. Mismanagement of sand resources is typically the cause of long-term, persistent beach erosion. The beaches downstream of Lake Worth Inlet in Florida are an example of how an inlet can induce beach erosion. Over the previous... Read More

Effects of Sowing Date on Growth and Production Parameters of the Rainfed Onion Variety Ares in Central and Northern Ivory Coast

Image This study was conducted in central and northern Ivory Coast, precisely in Yamoussoukro and Ferkessédougou with the onion variety Ares. The objective was to determine the best planting dates for rainfed onion production in each of the agro-ecological zones. Thus, five sowing dates were tested. In Yamoussoukro, sowing was carried out on 01 May (D1), 15 May (D2), 01 June (D3), 15 June (D4) and 01 July. In Ferkessédougou, sowing was carried out on 3 May (D1), 17 May (D2), 3 June (D3), 17 June (D4) and 3 July (D5). The parameters evaluated were the survival rate of the... Read More

Prognosis, Characteristics, Causation, and Medications of Sickle Cell Anaemia

Image Sickle cell disease, an inherited blood condition, manifests itself as sickle cell anaemia. Your red blood cells, which were once flexible discs, become hard and sticky as a result of sickle cell anaemia. Sickled cells prevent red blood cells from carrying out their job of distributing oxygen throughout your body. Sickled cells live less time than healthy red blood cells do. Anemia, the illness that gives sickle cell anaemia its name, results from your body's inability to produce enough healthy red blood cells. When sickle cell anaemia was present at birth, newborns had a very low adult survival rate.... Read More

Detailed explanation of factors that influence platelets

Image Small blood cells called platelets aid in the formation of clots by your body to halt bleeding. Your blood vessel will signal the platelets if it sustains damage. The platelets then hastily move to the damaged area and create a plug (clot) to repair the damage. Adhesion is the term used to describe the process of spreading across the surface of a broken blood vessel to halt bleeding. This is due to the sticky tentacles that platelets develop as they reach the damage site, which aid in their ability to stick (adhere) to one another. In order to draw... Read More

Significant view of conditions that affect platelets

Image Blood Disorders & Transfusion Journal is a peer reviewed and open access journal aimed to publish most interesting and complete reliable source of information on current development and advanced research findings in the mode of original articles, review articles, case reports, short communications, etc. in all areas of the field and making them freely available through online without any restrictions or any other subscriptions to researchers worldwide. Small blood cells called platelets aid in the formation of clots by your body to halt bleeding. Your blood vessel will signal the platelets if it sustains damage. The platelets then... Read More

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The neuropathological diagnosis of Alzheimer’s disease

Image Alzheimer’s disease is a progressive neurodegenerative disease most often associated with memory deficits and cognitive decline, although less common clinical presentations are increasingly recognized. The cardinal pathological features of the disease have been known for more than one hundred years, and today the presence of these amyloid plaques and neurofibrillary tangles are still required for a pathological diagnosis. Alzheimer’s disease is the most common cause of dementia globally. There remain no effective treatment options for the great majority of patients, and the primary causes of the disease are unknown except in a small number of familial cases driven by genetic... Read More

History of Giraffe

Image The giraffe (Giraffa) is an African artiodactyl mammal, the tallest dwelling terrestrial animal and the biggest ruminant. It is historically taken into consideration to be one species, Giraffe camelopardalis, with 9 subspecies. However, the lifestyles of as much as 9 extant giraffe species has been described, primarily based totally upon studies into the mitochondrial and nuclear DNA, in addition to morphological measurements of Giraffe. Seven different species are extinct, prehistoric species recognized from fossils. The giraffe's leader distinguishing traits are its extraordinarily lengthy neck and legs, its horn-like ossicones, and its one-of-a-kind coat patterns. It is classed beneath Neath the... Read More

Male Sperm Cryopreservation, SARS-CoV-2 Infection, and Male Fertility

Image SARS-CoV-2 is a novel β-Covid imparting 80% grouping homology to the prior SARS-CoV infection causing the SARS episode in 2003. Nonetheless, SARS-CoV-2 presents unmistakable attributes. Its 3D construction shows a more conservative setup, which expands its limiting liking for angiotensin changing over chemical 2 (ACE2) that fills in as a viral receptor. What's more, SARS-Cov-2 presents a polybasic (furin) cleavage site expanding the infection's capacity to disguise into cells. Every one of these highlights can clarify, in any event incompletely, the most grounded clinical effect when contrasted with the other Covid. ACE2 is profoundly communicated in a wide scope of... Read More

More talking, More problems: 'Cell phone elbow'

Image If your pinkie and ring fingers tingle or feel numb, you might not want to pick up that cell phone to call the doctor. Orthopedic specialists are reporting cases of "cell phone elbow," in which patients damage an essential nerve in their arm by bending their elbows too tightly for too long. When cell phone users hold the phone to their ears, they stretch a nerve that extends underneath the funny bone and controls the smallest fingers. When talkers chat for a long time in that position, it "chokes the blood supply to the nerves. It makes the nerves... Read More

Top-Down Analysis of Temporal Hierarchy in Biochemical Reaction Networks.

Image The investigation of dynamic elements of enormous scope organic organizations has increased as of late. A basic part in building up a comprehension of such elements includes the investigation of their various leveled association. We research the fleeting chain of command in biochemical response networks zeroing in on: (1) the clarification of the presence of "pools" (i.e., total factors) framed from segment focuses and (2) the assurance of their organization and connections throughout various time scales. To date the distinguishing proof of such pools without earlier information on their organization has been a test. Another methodology is created for the... Read More

Management of liver injuries

Image Management of liver injuries The liver is one of the most commonly injured organs in abdominal trauma. Recent advancements in imaging studies and enhanced critical care monitoring strategies have shifted the paradigm for the management of liver injuries. The liver is one among the foremost frequently injured organs in abdominal trauma. The anterior location within the abdomen and fragile parenchyma with easily disrupted Glisson’s capsule make this organ susceptible to injury. There is a paradigm shift within the management of liver trauma thanks to advancements of diagnostic and therapeutic modalities. A few century ago, Pringle conducted an... Read More

Improved eating quality of seafood: the link between sensory characteristics, consumer liking and attitudes

Image Improved eating quality of seafood: the link between sensory characteristics, consumer liking and attitudes Introduction: why is the eating quality important for the industry and for the consumer? Fish consumption varies greatly across Europe. Welch et al. provided an overview of the fish consumption in 10 European countries. The highest total fish consumption was in Spain, but the lowest in Germany and the Netherlands. However, generally more fish was consumed in Northern compared to Southern Europe. The proportion of fat fish species of the total consumption was relatively higher in coastal areas of Northern Europe, such as in Denmark and... Read More

Clustered regularly interspaced short palindromic repeats

Image Clustered regularly interspaced short palindromic repeats CRISPR (/ˈkrɪspər/) (which is an abbreviation for grouped consistently interspaced short palindromic rehashes) is a group of DNA arrangements found in the genomes of prokaryotic organic entities like microbes and archaea. These successions are gotten from DNA parts of bacteriophages that had recently contaminated the prokaryote. They are utilized to recognize and annihilate DNA from comparative bacteriophages during ensuing contaminations. Subsequently these groupings assume a critical part in the antiviral (for example hostile to phage) protection arrangement of prokaryotes and give a type of gained invulnerability. CRISPR are found in roughly half of... Read More

Thyroid Disease Diagnosis and Tests

Image Thyroid Disease Diagnosis and Tests How to do a self-exam of your thyroid. How is thyroid disease diagnosed? Sometimes, thyroid disease can be difficult to diagnose because the symptoms are easily confused with those of other conditions. You may experience similar symptoms when you are pregnant or aging and you would when developing a thyroid disease. Fortunately, there are tests that can help determine if your symptoms are being caused by a thyroid issue. These tests include: •           Blood tests. •           Imaging tests. •           Physical exams. Blood tests One of the most definitive ways to diagnose a thyroid problem is... Read More

Pharmacoepidemiology and Drug Safety

Image Pharmacoepidemiology and Drug Safety The objective of this study is Pharmacoepidemiology and Drug Safety. Pharmacoepidemiology and Drug Safety is to provide an international forum for the communication and evaluation of data, methods and opinion in the discipline of pharmacoepidemiology. The Journal publishes peer-reviewed reports of original research, invited reviews and a variety of guest editorials and commentaries embracing scientific, medical, statistical, legal and economic aspects of pharmacoepidemiology and post-marketing surveillance of drug safety. Pharmacoepidemiology is the study of the uses and effects of drugs in well-defined populations. To accomplish this study, pharmacoepidemiology borrows from both pharmacology and epidemiology. Thus, pharmacoepidemiology is the... Read More

Signs and symptoms : Crohn's disease

Image An aphthous ulcer on the mucous membrane of the mouth in Crohn's disease. Many people with Crohn's disease have symptoms for years before the diagnosis. The usual onset is in the teens and twenties, but can occur at any age. Because of the 'patchy' nature of the gastrointestinal disease and the depth of tissue involvement, initial symptoms can be more subtle than those of ulcerative colitis. People with Crohn's disease experience chronic recurring periods of flare-ups and remission. Abdominal pain is a common initial symptom of Crohn's disease, especially in the lower right abdomen. It is often accompanied by... Read More

Colorectal Cancer

Image A cancer of the colon or rectum, located at the digestive tract's lower end. Early cases can begin as non-cancerous polyps. These often have no symptoms but can be detected by screening. For this reason, doctors recommend screenings for those at high risk or over the age of 50. Colorectal cancer symptoms depend on the size and location of the cancer. Some commonly experienced symptoms include changes in bowel habits, changes in stool consistency, blood in the stool and abdominal discomfort. Colorectal cancer treatment depends on the size, location and how far the cancer... Read More

Emerging drugs for the treatment of anxiety

Image Anxiety disorders are among the most prevalent and disabling psychiatric disorders in the United States and worldwide. Basic research has provided critical insights into the mechanism regulating fear behavior in animals and a host of animal models have been developed in order to screen compounds for anxiolytic properties. Despite this progress, no mechanistically novel agents for the treatment of anxiety have come to market in more than two decades. The current review will provide a critical summary of current pharmacological approaches to the treatment of anxiety and will examine the pharmacotherapeutic pipeline for treatments in development. Anxiety and related... Read More

Role of Immunogenetics in anthropological studies

Image The genes cryptography for the most molecules concerned within the human immune system--immunoglobulins, human free phagocyte matter (HLA) molecules and killer-cell immunoglobulin-like receptors (KIR)--exhibit a awfully high level of polymorphism that reveals exceptional frequency variation in human populations. 'Genetic marker' (GM) allotypes placed within the constant domains of immunoglobulin antibodies are studied for over forty years through medical science typewriting, resulting in the identification of a spread of gram haplotypes whose frequencies vary sharply from one geographic area to a different. a powerful diversity of HLA alleles, which ends in aminoalkanoic acid substitutions placed within the antigen-binding region of HLA... Read More

Restenosis

Image Restenosis is the recurrence of stenosis, a narrowing of a blood vessel, leading to restricted blood flow. Restenosis usually pertains to an artery or other large blood vessel that has become narrowed, received treatment to clear the blockage and subsequently become renarrowed. This is usually restenosis of an artery, or other blood vessel, or possibly a vessel within an organ. Restenosis is a common adverse event of endovascular procedures. Procedures frequently used to treat the vascular damage from atherosclerosis and related narrowing and renarrowing (restenosis) of blood vessels include vascular surgery, cardiac surgery, and angioplasty. When a stent is used and restenosis occurs, this is called in-stent restenosis or ISR. If it occurs following balloon angioplasty, this... Read More

The hippocampus

Image The hippocampus Journal of Brain Behaviour and Cognitive Sciences is using Editorial Tracking System for quality in peer review process. Review process is performed by the editorial board members of Journal of Brain Behaviour and Cognitive Sciences or outside experts. https://www.imedpub.com/submissions/brain-behaviour-cognitive-sciences.html or send us as an e-mail attachment to jbbcs@eclinicalsci.com The hippocampus is a major component of the brain of humans and other vertebrates. Humans and other mammals have two hippocampi, one in each side of the brain. The hippocampus is part of the limbic system, and plays important roles in the consolidation of information from short-term memory to long-term memory, and in spatial memory that enables navigation. The hippocampus is located under... Read More

Science – No one knows its beginning point but trying to find the end point

Image Every analyst is looking for the end point. Be that as it may, nobody recognizes what's happening and not certain might be it resembles theory of the universe's origin. Obviously one can contend that it is a result of quality coding GATT GACTA AGAT nitrogen puts together thus with respect to likewise through record and interpretation systems that happen in an individual or a creature. Journal of Aging Science is endeavoring to uncover the refreshed data through open access distribution which means articles can be distributed at greatest limits where COVID-19 creation difficult stretches to researchers in research in... Read More

Cardiomyoplasty : A Brief

Image Cardiomyoplasty is a surgical procedure in which healthy muscle from another part of the body is wrapped around the heart to provide support for the failing heart.[1] Most often the latissimus dorsi muscle is used for this purpose. A special pacemaker is implanted to make the skeletal muscle contract. If cardiomyoplasty is successful and increased cardiac output is achieved, it usually acts as a bridging therapy, giving time for damaged myocardium to be treated in other ways, such as remodeling by cellular therapies CELLULAR CARDIOMYOPLASTY Cellular cardiomyoplasty is a method which augments myocardial function and cardiac output by directly growing new muscle cells in the damaged myocardium... Read More

Pathways of Communication during Crisis

Image Crisis brings danger and opportunity. The COVID-19 pandemic will go down in history as an unprecedented crisis in the modern world, causing disruption and high death rates in nearly every country. The long-term impact of the pandemic is yet to be assessed. There are fears of a second wave and of deepening economic recession. Social inequality has increased, but there are also local and national initiatives providing help to those most in need. Scientists are responding to the desperate calls for effective vaccines and medications. Many research studies are underway and the knowledge that is gathered is shared and expanded... Read More

Optic nerve disorder

Image The optic nerve is a bundle of more than 1 million nerve fibers. Nerve signals travel along the optic nerve from each eye and send visual information to the brain. Damage along the optic nerve pathway causes specific patterns of vision loss. The three types of vision loss caused by optic nerve disorders are: One eye or one optic nerve is damaged; vision loss occurs on the affected side. The optic chiasm, the space behind the eyes where the optic nerves meet, is damaged; vision in the outer part of both eyes is lost. If the visual pathways... Read More

Detection of Clinical Volatile Organic Component (VOC) for Biomedical Applications

Image Clinical Volatile Organic Compounds (VOCs) have generated increasing interest in biomedical research as they play a vital role in developing diagnostics, prognosis, and therapeutics for a disease or indisposition. VOCs may be an endogenous product of the metabolic processes or produced due to an extraneous challenge such as the presence of microbial population or pollutants. Emerging analytical methodology for collecting, preconcentrating, and analyzing VOCs allows us to detect a comprehensive list of clinical VOCs and provide a confident identification of the VOCs sample from different health status. Associating chemical knowledge of VOCs with the cellular mechanism and leveraging that understanding... Read More

Energy and Environmental Security

Image Energy and environmental security are some of the most important issues on the US national security agenda. Some scholars have argued that security starts with the environment. The chapter begins focusing on some of the recent trends in energy consumption, particularly oil and natural gas. The chapter explores hydraulic fracturing, or fracking, which is a hotly debated method for extracting natural gas. This section also examines the Obama administration’s energy security policy. Next, the chapter focuses on major trends in pollution, which has impacted climate change. This work highlights the Obama administrations responses to climate change, focusing on the major... Read More

COMPUTED CHEST RADIOGRAPHS

Image On behalf of the journal of clinical radiology and case reports: Open Access, as Editor-in-Chief, it is my distinct honour and privilege to inform you that, it’s been Four long years we have started the Journal, now we are celebrating the 4th Anniversary and we are privileged to welcome clinical Society to our journal. As Editor-In-Chief it is my great pleasure and honour to welcome you to the Journal of clinical radiology and case reports: Open Access. The journal of clinical radiology and case reports: Open Access aims to disseminate knowledge and promote discussion... Read More

Introduction of Benign tumor

Image Introductio to  Benign Tumor   A benign tumor is a mass of cells (tumor) that lacks the ability to either invade neighboring tissue or metastasize (spread throughout the body). When removed, benign tumors usually do not grow back, whereas malignant tumors sometimes do. Unlike most benign tumors elsewhere in the body, benign brain tumors can be life-threatening. Benign tumors generally have a slower growth rate than malignant tumors and the tumor cells are usually more differentiated (cells have more normal features). They are typically surrounded by an outer surface (fibrous sheath of connective tissue) or stay contained within the epithelium. Common examples of benign tumors include moles and uterine fibroids. Although benign... Read More

Blau syndrome.

Image Blau Syndrome is an autosomal dominant genetic inflammatory disorder that affects the skin, eyes, and joints. It is caused by a mutation of the NOD2 (CARD15) gene. Symptoms typically starting before 4 years of age, with early onset of skin sarcoidosis, granulomatous arthritis, and uveitis. Elucidation that the gene deficiency in BS includes the CARD15/NOD2 gene has prompted many investigators to identify how this gene functions as part of the innate immune system that reacts to bacterial polysaccharides, such as muramyl dipeptide, to induce signaling pathways that cause cytokine reactions and to protect the organism. Treatment has included the usual... Read More

Chronic Inflammatory Arthritis

Image Chronic Inflammatory Arthritis Fiery joint pain is the name used to depict a gathering of illnesses brought about by an overactive invulnerable framework that outcomes in irritation. Numerous types of these ailments show predominantly with aggravation of the joints felt as joint torment and firmness, yet incendiary joint pain can likewise influence other connective tissues, including the lungs, heart, eyes, skin and different organs. Critically, when irritation influences any piece of the body it can bring about harm which is irreversible. In common circumstances, the body reacts to contamination or the nearness of an outside substance, for example, microbes, an... Read More

Inflammation: Skin Infection

Image A skin infection is an infection of the skin in humans and other animals, that can also affect the associated soft tissues such as loose connective tissue and mucous membranes. They comprise a category of infections termed skin and skin structure infections (SSSIs), or skin and soft tissue infections (SSTIs), and acute bacterial SSSIs (ABSSSIs). They are distinguished from dermatitis (inflammation of the skin). Although skin infections can result in skin inflammation. Fungal: Fungal skin infections may present as either a superficial or deep infection of the skin, hair, and/or nails. As of 2010, they affect about one billion people... Read More